Essay examples --

It is already well known that treating LPS to RAW 264.7 cells outgrowths both(prenominal) the last mentioneds duration and muster up area, as the former is accepted by the latter as a PAMP (Christie). While the general direction of morphological metamorphose was predicted, its degree with respect to the concentration of LPS source tough still remained in question. Thus, the investigation assessed the following two aspects of morphological change compared to their negative tally radicals Difference in average length and surface area of RAW 264.7 cells.As shown in Figure 3 of this investigation, a positive correlation exists surrounded by the concentration of LPS solution treated and the deflection in average length of RAW 264.7 cells compared to that of those of the negative control group for instance, the latter increase from 14.385 m to 53.763 m as the former change magnitude from 0.1 gml-1 to 100 gml-1. The latters magnitude of increase decreased with each increase in the former, exhibiting the correlations logarithmic behavior compared to the latters increase from 25.215 m to 44.001 m as the former increased from 1 gml-1 to 10 gml-1, the latters increase from 44.001 m to 53.763 m as the former increased from 10 gml-1 to 100 gml-1 was marginal. The overall correlation between the two variables shown is strong, as evidenced by its high correlation coefficient rate (R2=0.9846) and the absence of outliers throughout the data.Figure 4 of this investigation also displays a positive correlation between the concentration of LPS solution treated and the contrariety in average surface area of RAW 264.7 cells compared to that of those of the negative control group for instance, the latter increased from 55.714 m2 to 277.400 m2 as the former ... ...ral weaknesses were considered. For instance, fractures in cytoplasmic processes most likely have originated from physical damage rather than from immunologic interactions repeated attempts to attach coversl ips onto the SEM specimen stubs using carbon adhesive tabs seems to be the cause.Nevertheless, previous studies on relevant fields show that some system factors involved in TLR4 signaling pathway whitethorn regulate LPS-induced apoptosis in macrophages (Ma et al. 41827). Connections could thus be drawn between the concentration of LPS solution treated and RAW 264.7 cell death to some degree. The existence of a threshold value for LPS concentration to induce cell death may also explain the logarithmic correlations seen in differences in average length and surface area of RAW 264.7 cells, suggesting a limit to which the cells can reduce immunologic responses.